Clinton was on her way to the White House when she fell and injured her elbow, chief of staff Cheryl Mills said in a statement released late Wednesday.
Clinton was treated at The George Washington University Hospital, just a few blocks from State Department headquarters, before going home. She will undergo surgery to repair her elbow in the coming week, Mills said.
"Secretary Clinton appreciates the professionalism and kindness she received from the medical team who treated her this evening and looks forward to resuming her full schedule soon," Mills said.
Clinton had been scheduled to join actress Angelina Jolie on Thursday morning at a Washington event marking World Refugee Day. That event has been removed from Clinton's public schedule.